24/04/25
19:21:44
Laboratory of Mathematic methods and models in bioinformatics,
Institute for Information Transmission Problems,
Russian Academy of Sciences

Scientific and Educational Work

Laboratory 6 was established by a resolution of the Academic Council of IITP RAS in January 2004, based on Sector 1.1 founded in 1998. The Laboratory continues its prior research themes: studies in algorithmic models and methods for efficient description of objects and processes, which have been conducted for the past 50 years, as well as research in mathematical biology and bioinformatics initiated within this team in 1995.

Over the last five years, the Laboratory’s staff have published over 100 papers in leading national and international journals, along with several monographs. Staff members participate in international conferences on mathematics, mathematical biology, and bioinformatics, and regularly visit leading foreign universities for collaborative research and lectures. The Laboratory has supervised the defense of 2 doctoral (DSc) and 5 candidate (PhD) dissertations, and has conducted research under dozens of national and international grants and projects.

The Laboratory’s work focuses on two main areas:

  1. Information processes at molecular and cellular levels;
  2. Problems of discrete and multicriteria optimization, development of efficient algorithms and models, and questions of decidability and expressiveness in formalized theories, including the broadest of them — set theory.

The primary objective of the Laboratory in area (I) is the development of mathematical methods and models in mathematical biology and bioinformatics, applied to the following problems:

  1. Identification of gene expression regulation at transcriptional, translational, and post-transcriptional levels;
  2. Elucidation of regulatory mechanisms;
  3. Study of the evolution of regulatory systems — in bacteria, plants, algae, protozoa, and their organelles, including plastids and mitochondria;
  4. Gene evolution, species evolution, and their co-evolution;
  5. Origins of species, roles of horizontal gene transfer and other evolutionary events in genome formation.

The average age of the Laboratory’s staff is ~50 years. The full list of publications is available in the Publications section.

The Laboratory’s staff includes official experts of the Russian Academy of Sciences (RAS), Russian Science Foundation (RSF), Skolkovo Foundation, and the Ministry of Science and Higher Education. Staff members are engaged in teaching (lectures, seminars, undergraduate and graduate supervision) at Lomonosov Moscow State University (Mechanics and Mathematics Faculty, Faculty of Computational Mathematics and Cybernetics), Moscow State Pedagogical University, and Moscow State University of Design and Technology. The Laboratory also collaborates closely with the Research Center for Electronic Computing Machinery. Staff members serve on two dissertation councils in Computer Science and Mathematical Biology/Bioinformatics.